Social scientists increasingly acknowledge that explanations of social behavior can be improved by drawing on data and models from the biological sciences to better understand the microfoundations of human behavior. At the same time, life scientists have become aware that macro-models of societal behavior, developed by social scientists, can inform their understanding of how biology affects social behavior. In addition, social scientists seeking to explain the factors influencing health outcomes, including depression and anxiety, have found that advances in biology give them access to means of measurement that have not been previously available. Yet, the complex and multivalent relationship between the life sciences and the social sciences is still largely unexplored. The University of Illinois has launched an initiative to be a global leader in this emerging area of research. This search invites applications from various fields in the social sciences whose research agenda engages the biological sciences, broadly defined.